Synthesis and Molecular Docking Study of Arylsulfanyl Pyrazolylpyrazoline Derivatives as Antitubercular Agents

New arylsulfanyl pyrazolylpyrazoline derivatives were synthesized via a facile protocol, and their structure was confirmed by FT-IR, 1H and 13C NMR, and mass spectra. Some of the synthesized compounds exhibited remarkable in vitro antitubercular activity. Molecular docking study provided well-clustered solutions to the mode of binding and affinity of these molecules to the active site of MTB enoyl–acyl carrier protein reductase (InhA).