TB Research

P5‐35: Successful treatment of disseminated nontuberculous infection with <i>Mycobacterium genavense</i> mimicking malignancy in a patient with anti–interferon‐gamma (IFN‐Γ) autoantibodies

Respirology · 2021-11

Abstract

Subjects and Methods: We retrospectively studied 351 COVID-19 patients (178 males and 173 females, mean age 59.3 years) admitted to our hospital between April 3, 2020, and May 31, 2021.According to the severity of illness classification by the National Institutes of Health (NIH), USA, the cases were classified into four groups (mild, moderate, severe, and critical).A comparative study was conducted on background factors such as underlying diseases, clinical test values, and the spread of opacity in computed tomography (CT) chest imaging.Results: Exacerbation factors included age, underlying diseases (diabetes mellitus, interstitial pneumonia), low lymphocyte count, high D-dimer values, and the extent of opacity on CT chest imaging.Multivariate analysis revealed concomitant diabetes mellitus and a wider area of opacity on CT chest imaging as independent exacerbation factors.

MeSH terms

  • Medicine
  • Nontuberculous mycobacteria
  • Malignancy
  • Interferon γ
  • Autoantibody
  • Interferon gamma
  • Immunology