TB Research

Features of the clinical course of coronavirus and bacterial pneumonia

А. Yu. Kraposhina, Н. В. Гордеева, Ирина Демко, I. A. Soloveva, M. G. Mamaeva, Е. А. Собко, Е. A. Verbitskaya, Ksenia Shadrina

Abstract

<bold>Purpose:</bold> to identify the features of the clinical course of bacterial and Covid-19 pneumonia. Materials and methods: retrospective analysis of 547 medical histories of patients from Krasnoyarsk Regional clinical hospital with an established diagnosis of pneumonia aged 18 to 95 years. They were divided into 2 groups: 1 group - 336 patients with Covid-19 pneumonia and 2 group - 211 patients with community-acquired bacterial pneumonia. <bold>Results:</bold> No polo-age differences were identified between patients with Covid-19 and bacterial pneumonia. Covid-19 pneumonia is more characterized by bilateral lung damage (84% of patients in 1 group, 12% of patients in 2 group, p<0.05). Typical clinical symptoms in patients with Covid-19 pneumonia were: fever 100%, dry cough 98%, anosmia 97%, pronounced general weakness 94%, shortness of breath 76%, respiratory failure 62%. Typical clinical symptoms in patients with community-acquired pneumonia of bacterial etiology were: fever 100%, productive cough with sputum 83%, pronounced overall weakness 64%. Patients of 1 group are characterized by a decrease in blood potassium, a more pronounced acceleration of blood sedimentation rate by 1.75 times, an increase in CRP by 5.7 times, the content of white blood cells within the norm is either reduced, while patients of 2 group are characterized by the presence of leukocytosis, normal potassium and lower blood sedimentation rate (р<0.05). <bold>Measurements and Main Results:</bold> Patients with Covid-19 associated pneumonia have more severe clinical features: bilateral lung involvement is more often detected, characteristic changes in the blood: lymphopenia, significant increase of blood sedimentation rate, hypopotassemia, significant increase in CRP.

MeSH terms

  • Medicine
  • Pneumonia
  • Internal medicine
  • Erythrocyte sedimentation rate
  • Sputum
  • Community-acquired pneumonia
  • Gastroenterology
  • Leukocytosis
  • Bacterial pneumonia
  • Lung