The non-tuberculous pulmonary disease experience in a general respiratory clinic in the UK
Yadee Myint, Sachin Ananth, Cassandra Stavropolous, Jacob Anitha, Madhuri Vidwans, Pancha Nandasiri, Ajitha Jayaratnam
Abstract
<b>Introduction:</b> Identifcation of non-tuberculous mycobacterium pulmonary disease (NTM-PD) is challenging as culture confirmation of the NTM organism can be difficult. In addition, treatment is not straightforward due to the prolonged treatment course and potential drug toxicity. The incidence of NTM pulmonary disease in a respiratory clinic in Hertfordshire was measured along with associated patient characteristics and outcomes. <b>Methods:</b> The notes for patients with respiratory microbiology specimens culturing a non-tuberculous mycobacterium species were reviewed from 2018 - 2019. Epidemiological details and clinical details of patients including treatment were collected. <b>Results:</b> 93 patients were identified with sputum or bronchial wash cultures of NTM. Mean age was 67 years. 61% of patients had underlying respiratory disease. 25% received treatment. <b>Conclusion:</b> Isolation of an NTM species in sputum or bronchial wash does not always indicate significant NTM-PD and need treatment. The majority of patients where an NTM was cultured did have underlying lung disease. Further review is needed to investigate whether criteria for treatment were met in th e group when an NTM species was cultured.
MeSH terms
- Medicine
- Sputum
- Disease
- Isolation (microbiology)
- Respiratory system
- Incidence (geometry)
- Respiratory disease
- Epidemiology
- Pulmonary disease
- Lung disease
- Internal medicine
- Sputum culture
- Tuberculosis
- Lung