An Unusual Presentation of Disseminated Tuberculosis in South-West Nigeria: A Case Report
Martins Ehizode Emuze, Arinola Esan, Oladotun Olalusi, Omolade O. Adegoke, Temitope E Ogunsanya, Chima Akunwata, John C. Akulue
Journal of Infectious Diseases and Epidemiology · 2021-11
Abstract
Disseminated tuberculosis is a leading cause of morbidity and mortality in developing nations. It could be a diagnostic challenge because of the nonspecific manifestations and sometimes atypical laboratory and radiologic findings. It results from haematogenous spread of <em>Mycobacterium tuberculosis</em> in 2 or more noncontiguous sites. Clinical features may include fever, weight loss, anorexia, anemia, pancytopenia, hepatosplenomegaly and most times, patients have elevated inflammatory markers like erythrocyte sedimentation rate (ESR). Delay in diagnosis and treatment could portend a poor clinical outcome for the patient. Therefore, a high index of suspicion is crucial for early diagnosis and management.
MeSH terms
- Hepatosplenomegaly
- Pancytopenia
- Medicine
- Tuberculosis
- Erythrocyte sedimentation rate
- Anorexia
- Anemia
- Pediatrics
- Mortality rate
- Weight loss
- Mycobacterium tuberculosis
- Surgery
- Intensive care medicine