TB Research

Prevalence and diagnostic validity of chest tomography findings in patients with suspected active pulmonary tuberculosis

Ángela María Giraldo Montoya, Giovanni García Castro, Juan José Gutierrez Paternina, Ángela María Giraldo Montoya

Abstract

<b>Introduction:</b> The performance of diagnostic tests for tuberculosis (TB) varies depending on the prevalence of the disease. A research project was proposed to describe the tomographic findings of a group of patients with suspected tuberculosis in an endemic area and were contrasted with the culture results for Mycobacterium tuberculosis. <b>Methodology:</b> A study for the evaluation of diagnostic, retrospective, observational and descriptive tests was designed. Variables were obtained from clinical histories and chest tomography images over a period of 4 years. The diagnostic performance for each tomographic finding was calculated and with the best, a parallel analysis was developed. <b>Results:</b> 628 records and 880 cultures for M. tuberculosis were distributed as well; sputum (47%), bronchoalveolar lavage (33.7%), tracheal aspirate (5.5%) others (13.8%). The most prevalent findings were: free pleural effusion (50.3%) consolidation and fibrotic tracts (33.5%). The best diagnostic performance was micronodular opacities, tree in bud, apical cavitation and the nodule (table 1). <b>Conclusions:</b> For the sample studied, the absence of micronodular opacity, budding tree, apical cavitation and nodule in the chest tomography can rule out active pulmonary tuberculosis in 89.4% of cases

MeSH terms

  • Medicine
  • Tuberculosis
  • Bronchoalveolar lavage
  • Sputum
  • Pleural effusion
  • Mycobacterium tuberculosis
  • Radiology
  • Tomography
  • Retrospective cohort study
  • Pulmonology
  • Sputum culture
  • Lung