TB Research

Cytokine storm in tuberculosis and IL-6 involvement

Funmilayo Grâce Boni, Insaf Hamdi, Liadrine Moukendza Koundi, Kanchan Shrestha, Jianping Xie

Infection Genetics and Evolution · 2021-11

Abstract

Tuberculosis is probably the most seasoned illness of the humanity. Intricacies or subsequent death emerging from these infections are frequently connected with cytokine storm. Interleukin-6 (IL-6) plays a crucial role in the immune response to tuberculosis. Therefore, there is a need to research some new therapeutic approaches to block IL-6 signaling that are right now being applied to the M. tuberculosis. In this review, we investigate the implication of IL-6 in the context of tuberculosis research.

MeSH terms

  • Tuberculosis
  • Biology
  • Cytokine storm
  • Immunology
  • Context (archaeology)
  • Cytokine
  • Immune system