Tuberculosis and Guillian Barre Syndrome – A Rare Presentation of AMAN Variant

A 57-year female resident of U.P. presented with acute-onset quadriparesis that had developed during last 5 days along with breathlessness. After extensive clinical, laboratory and radiological evaluation, the patient was diagnosed with an acute motor axonal neuropathy (AMAN) variant of Guillain-Barre Syndrome (GBS). Treatment was given as per the protocol, simultaneously diagnosed to have tubercular meningitis for which first-line Anti-Tubercular Therapy was administered. During the follow-up at 6 months, the patient was asymptomatic, she had no residual weakness and could walk without support, and tuberculosis had resolved. Many infectious agents have been known to trigger GBS, but only a few cases of GBS and Tuberculosis have been reported. This association needs to be evaluated and must be kept in mind in TB prevalent nations.