TB Research

Study on Serum Zinc Levels and Vitamin a Levels in Tuberculosis Patients

Gangaram Bhadarge, Nandkishor Bankar, Sudhir Singh

Journal of Pharmaceutical Research International · 2021-07

Abstract

Introduction: Tuberculosis, an infectious disease caused by the bacteria Mycobacterium tuberculosis (MTB), is also a major cause of death in humans around the world. According to a World Health Organization (WHO) survey, MTB infects one-third of the world's population, with 9.6 million new tuberculosis (TB) infections and 1.5 million deaths confirmed this in 2021
 Aim: study of serum zinc levels and vitamin a levels in tuberculosis patients.
 Materials and Methods: This study included 40 newly diagnosed PTB patients of both sex with the age group of 18-60.Time period of this study was from September 2020 to Арril 2021 а nоn-rаndоmised соntrоlled trial was involved.
 Result: There was a strong correlation between serum zinc and vitamin A levels P < 0.01) Hb, P < 0.01) and serum albumin levels P < 0.01) were also strongly correlated with the vitamin A levels; however, WBC P < 0.01) and ESR P < 0.01) were negatively correlated with the vitamin A levels.
 Conclusion: In view of the above, the patient's nutritional status may be the most important determinant of infection tolerance. Zinc deficiency can have an indirect impact on Vitamin A metabolism by reducing the levels of circulating protein. Because of this, the addition of zinc in combination with vitamin A may be helpful in achieving the disease status.

MeSH terms

  • Tuberculosis
  • Mycobacterium tuberculosis
  • Medicine
  • Vitamin
  • Zinc deficiency (plant disorder)
  • Zinc
  • Vitamin D and neurology
  • Population
  • Disease
  • Internal medicine
  • Physiology
  • Immunology