TB Research

Mycobacterium Avium Complex Infection as a Rare Cause of Cerebral Mass Lesion and IRIS in a Patient with AIDS: Case Report and Review of the Literature

Courtney Lane‐Donovan, Emma Bainbridge, John D. Szumowski, Andrew D. Kerkhoff, Michael J. Peluso

Open Forum Infectious Diseases · 2021-10

Abstract

Abstract A patient with advanced HIV/AIDS presented with a brain abscess. While brain biopsy culture and pathology were unrevealing, universal broad-range PCR (uPCR) demonstrated Mycobacterium avium complex (MAC). We review the clinicopathologic characteristics of MAC brain abscesses and highlight the effectiveness of uPCR as a diagnostic tool in partially-treated infections.

MeSH terms

  • Medicine
  • Mycobacterium avium complex
  • IRIS (biosensor)
  • Lesion
  • Mass/lesion
  • Pathology
  • Mycobacterium