Cytomegalovirus Infection Is Associated With Increased Prevalence of Latent Tuberculosis Infection
Yuri F. van der Heijden, Bin Zhang, Claire Chougnet, Moisés A. Huamán
Open Forum Infectious Diseases · 2021-10
Abstract
Abstract Cytomegalovirus (CMV) increases tuberculosis (TB) risk, but its relationship with latent TB infection (LTBI) is unknown. Using US nationally representative data, we report that CMV was independently associated with LTBI (odds ratio, 2.94; 95% CI, 1.19–7.28; P=.02). CMV and LTBI were associated with higher C-reactive protein, suggesting chronic inflammation.
MeSH terms
- Medicine
- Latent tuberculosis
- Cytomegalovirus infection
- Cytomegalovirus
- Tuberculosis
- Odds ratio
- Immunology
- Internal medicine
- Human immunodeficiency virus (HIV)
- Mycobacterium tuberculosis