TB Research

Antibiotic resistance of non-fermenting Gram-negative bacilli isolated at a large Infectious Diseases Hospital in North-Eastern Romania, during an 11-year period

Elena Roxana Buzilă, Eduard Vasile Năstase, Cătălina Luncă, Aida Corina Bădescu, Egidia Miftode, Luminița Smaranda Iancu

GERMS · 2021-09

Abstract

INTRODUCTION: Increased antibiotic resistance of non-fermenting Gram-negative bacilli (NFGNB) associated with increased morbidity and mortality makes the infections they produce a major public health problem. This study aims to assess the evolution of antibiotic susceptibility and the level of NFGNB antibiotic resistance. METHODS: We carried out a retrospective study on 994 NFGNB strains which had been isolated in the Clinical Laboratory of the "Sf. Parascheva" Clinical Hospital of Infectious Diseases, Iaşi, during a period of 11 years (2008-2018). RESULTS: spp. The percentage of resistant strains was significantly higher in tracheobronchial aspirate compared to sputum. CONCLUSIONS: and that the use of medical devices can favor the occurrence of infections with multidrug-resistant strains.

MeSH terms

  • Pseudomonas aeruginosa
  • Acinetobacter
  • Antibiotics
  • Microbiology
  • Colistin
  • Sputum
  • Antibiotic resistance
  • Bacilli
  • Biology
  • Acinetobacter baumannii
  • Medicine