TB Research

Role of Fine Needle Aspiration Cytology in Effective Management of Patients with Granulomatous Inflammation in Neoplastic and Non-Neoplastic Lesions

Drashti Jay Patel, Ashwini Shukla, Toral Jivani

Tropical Journal of Pathology and Microbiology · 2021-05

Abstract

Background: Granulomatous inflammation is a common diagnosis given in fine-needle aspirationcytology (FNAC) and it is a type of chronic inflammation in which tissue reaction appears followingcell injury. Aims: To assess the usefulness of the cytological study in the diagnosis of granulomatouslesions. Materials and Methods: An observational study is done based on cytomorphologicalevaluation of 156 cases of granulomatous inflammation diagnosed at the Department of Pathology,in Surat Municipal Institute of Medical Education & Research over 18 months from February 2018 toJuly 2019. Results: Out of the total of 156 cases of granulomatous inflammation, tuberculosis wasthe most common finding in 111 cases (71.15%), followed by fungal infection (05 cases). The maleto female ratio was 1.0 to 1.4. The most commonly affected age group was 21 to 30 years.Conclusions: All the cases of granulomatous inflammations are analysed for definitive diagnosis toprovide early and proper treatment of underlying diseases, malignancies or lymphoma.

MeSH terms

  • Granulomatous inflammation
  • Medicine
  • Tuberculosis
  • Inflammation
  • Granuloma
  • Cytology
  • Pathology
  • Sarcoidosis
  • Lymphoma
  • Fine-needle aspiration
  • Histiocyte
  • Dermatology