TB Research

Presumed cytomegalovirus retinitis in a non-immune compromised patient with breast carcinoma during treatment: A case report

Chia-Chen Kao, Shiuh‐Liang Hsu, Shwu‐Jiuan Sheu

American Journal of Ophthalmology Case Reports · 2021-07

Abstract

PURPOSE: Cytomegalovirus (CMV) retinitis is one of the most common opportunistic infections in immunocompromised patients, including patients with acquired immunodeficiency syndrome (AIDS). CMV retinitis in non-human immunodeficiency virus (HIV)-infected patients has been reported with variable presentations. Significant intraocular inflammation is common, and visual prognosis is poor if not properly managed. OBSERVATIONS: We present a case of presumed CMV retinitis in a non-immunocompromised breast cancer patient that occurred during cancer treatment. The ocular symptoms developed one day after partial mastectomy with intra-operative radiotherapy following five months of chemotherapy treatment. Ocular manifestations included panuveitis with mild peripheral retinitis. CONCLUSIONS AND IMPORTANCE: Early diagnosis and prompt treatment with oral valganciclovir based on the clinical manifestation and serologic test findings helped to preserve vision.

MeSH terms

  • Medicine
  • Retinitis
  • Valganciclovir
  • Cytomegalovirus retinitis
  • Cytomegalovirus
  • Dermatology
  • Uveitis
  • Foscarnet
  • Tuberculosis
  • Ganciclovir
  • Surgery
  • Immunology
  • Human cytomegalovirus