Assessment of clinical profile of multi drug resistant tuberculosis patients

Background: Drug-resistant tuberculosis (DR-TB) has become a significant public health problem in number of countries and one of the major obstacles in effective tuberculosis control programme. The present study was conducted to assess clinical profile of multi drug resistant tuberculosis patients.Materials & Methods: 82 patients of drug resistant TB of both genders were included and all were subjected to chest X-ray and mantoux test. Assessment of clinical features, type and treatment outcome was recorded.Results: Out of 82 patients, males were 52 and females were 30. Clinical features were fever in 69, cough in 56, loss of appetite in 28, loss of weight in 14 and past history in 6. Type of drug resistance was contact with partial XDR in 10, MDR in 6, MDR with contact in 30 and partial XDR in 36 patients. Type of tuberculosis was pulmonary TB in 40, disseminated TB in 26, TB lymphadenopathy in 9 and abdominal TB in 7 cases. The difference was significant (P