Design, synthesis and evaluation of novel indole-2-carboxamides for growth inhibition of <i>Mycobacterium tuberculosis</i> and paediatric brain tumour cells
Shahinda S. R. Alsayed, Shichun Lun, Anders W. Bailey, Amreena Suri, Chiang‐Ching Huang, Mauro Mocerino, Alan D. Payne, Simone Treiger Sredni, et al. (10 authors)
RSC Advances · 2021-01
Abstract
(viability) = 119 μM]. This suggests that an indoleamide scaffold can be fine-tuned to confer a set of derivatives with selective antitubercular and/or antitumour activities.
MeSH terms
- Indole test
- Mycobacterium tuberculosis
- Tuberculosis
- Chemistry
- Microbiology
- Combinatorial chemistry
- Pharmacology
- Stereochemistry
- Medicine