Comparative Genomic Analysis of <i>Mycobacteriaceae</i> Reveals Horizontal Gene Transfer-Mediated Evolution of the CRISPR-Cas System in the Mycobacterium tuberculosis Complex
Anoop Singh, Mohita Gaur, Vishal Sharma, Palak Khanna, Ankur Bothra, Asani Bhaduri, Anupam Kumar Mondal, Debasis Dash, et al. (10 authors)
mSystems · 2021-01
Abstract
Comparative genomic analysis of prokaryotes has led to a better understanding of the biology of several pathogenic microorganisms. One such clinically important pathogen is M. tuberculosis , the leading cause of bacterial infection worldwide.
MeSH terms
- Horizontal gene transfer
- CRISPR
- Mycobacterium tuberculosis
- Biology
- Gene
- Pathogen
- Tuberculosis
- Genetics
- Microbiology
- Opportunistic pathogen
- Mycobacterium tuberculosis complex
- Computational biology