<i>De Novo</i> Cobalamin Biosynthesis, Transport, and Assimilation and Cobalamin-Mediated Regulation of Methionine Biosynthesis in Mycobacterium smegmatis
Terry Kipkorir, Gabriel T. Mashabela, Timothy J. de Wet, Anastasia Koch, Stephanie S. Dawes, Lubbe Wiesner, Valerie Mizrahi, Digby F. Warner
Journal of Bacteriology · 2021-01
Abstract
Alterations in cobalamin-dependent metabolism have marked the evolution of Mycobacterium tuberculosis into a human pathogen. However, the role(s) of cobalamin in mycobacterial physiology remain poorly understood.
MeSH terms
- Cobalamin
- Methionine synthase
- Mycobacterium smegmatis
- Biology
- Biochemistry
- Biosynthesis
- Methionine
- Cofactor
- Enzyme