TB Research

Prevalence of latent tuberculosis and associated factors in patients with chronic kidney disease on hemodialysis

Ferreira V, Fonseca CDD, Bollela VR, Romão EA, Costa JACD, Sousa AFL, Barbosa DA

Revista latino-americana de enfermagem · 2021-07

Abstract

Objective to identify the prevalence of latent tuberculosis in patients with chronic kidney disease on hemodialysis and associated factors. Method a cross-sectional study conducted with 176 patients with chronic kidney disease on hemodialysis. The tuberculin test was performed with the standardized antigen, distributed by the Brazilian Ministry of Health, and the reading occurred after 72 to 96 hours of the application. An association test (Chi-square, Fisher's exact), prevalence ratio, and multivariate regression tests were performed. Results the prevalence of latent tuberculosis diagnosed through Tuberculosis Skin Test was 8.5% (15/176). The "has/has had diabetes" (aOR: 0.117; 95%CI: 0.015-0.92) and "having regular garbage collection (aOR: 0.076; 95%CI: 0.008-0.702) factors were associated with a lower probability of having a Positive skin test. Conclusion the low prevalence of latent tuberculosis identified and the factors associated with it reinforce the need for screening for latent tuberculosis infection for diabetics combined with an analysis of previous risk factors and comorbidities.

MeSH terms

  • Humans
  • Renal Dialysis
  • Prevalence
  • Risk Factors
  • Cross-Sectional Studies
  • Brazil
  • Renal Insufficiency, Chronic
  • Latent Tuberculosis