Treatment outcomes of drug susceptible Tuberculosis in private health facilities in Lagos, South-West Nigeria.

<strong>Abstract<br> Objective: </strong>The Lagos State Tuberculosis, Buruli Ulcer, and Leprosy Control Program<br> (LSTBLCP) started engaging private hospitals under the Public-Private Mix (PPM)<br> Program in 2008. The study aimed to evaluate the trend and predictors of successful<br> Tuberculosis (TB) treatment outcomes of patients managed across these private health<br> facilities between 2010-2016 in Lagos, Nigeria. <strong>Method: </strong>Retrospective review of TB treatment register and treatment cards of patients<br> commenced on TB treatment between January 2010 and December 2016 in 36 private<br> health facilities engaged by the LSTBLCP. Between December 2016 and February<br> 2017, data were collected and entered into Microsoft Excel by trained data entry clerks.<br> The analysis was done using SPSS software. Independent predictors of successful<br> treatment outcomes were determined using multivariate analysis at the statistical<br> significance of p&amp;lt;0.05 and 95% confidence interval. <strong>Results: </strong>A total of 1660 records of TB patients were reviewed. 1535 (92.47%)<br> commenced treatment, while 1337 (87.10%) of all records had documented treatment<br> outcomes. Of the 1337 patients with outcomes, 1044 (78.09%) had a successful<br> treatment outcome, and 293 (21.91%) had an unsuccessful outcome . Majority were<br> male, 980 (59.04%), Human Immunodeficiency Virus (HIV) negative status, 1295<br> (80.24%) , diagnosed with smear, 1141 (73.14%), treated in private not-for-profit<br> (PNFP) hospital, 1097 (66.08%), treated for TB between 2014-2016 (18.96%-19.52%).<br> In multivariate analysis, age&amp;gt;20years (aOR=0.26, p=0.001), receiving TB treatment in<br> 2013 (aOR=0.39, p=0.001), having genexpert for TB diagnose(aOR=0.26, p=0.031) and<br> being HIV positive (aOR=0.37, p=0.001) significantly reduced likelihood of successful<br> treatment outcome. The site of TB, being on ART or CPT, were confounding<br> determinants of successful treatment outcomes as they became non-significant at the<br> multivariate analysis level.