The preliminary comparative results between Covid-19 and non-Covid-19 patients in Western China

Abstract Background: This study aims to investigate the comparative clinical characteristics of Covid-19 and non-Covid-19 patients. Methods: Fifteen Covid-19 and 93 non-Covid-19 patients were included in RNA testing. All epidemiological and clinical data were collected and analyzed, and then comparative results were carried out. Results: Covid-19 patients were older (46.40±18.21 years vs 34.43±18.80 years) and hada higher body weight (70.27±10.67 kg vs 60.54±12.33 kg, P <0.05). The main symptoms that were similar between Covid-19 and non-Covid-19 patients, and Covid-19 patients showed a lower incidence of sputum production (6.67% vs 45.16%, P <0.01) and a lower white-cell count (4.83×10 9 /L vs 7.43×10 9 /L) and lymphocyte count (0.90×10 9 /L vs 1.57×10 9 /L) ( P <0.01). Although there were no differences, C-reactive protein and interleukin-6 were elevated in Covid-19 patients. The sensitivity and negative predictive value of CT images were 0.87 and 0.97, respectively. Covid-19 patients showed a higher contact history of Wuhan residents (80% vs 30.11%) and higher familial clustering (53.33% vs 8.60%, P <0.001). Covid-19 patients showed a higher major adverse events (ARDS, 13.33%; death, 6.67%; P <0.05). Conclusion: Our results suggested that Covid-19 patients had a significant history of exposure and familial clustering and a higher rate of severe status; biochemical indicators showed lymphocyte depletion.