TB Research

Brief Study on Antibiotics Rifampin, Ethambutol, Pyrazinamide. Isoniazid for the Treatment of Tuberculosis Patient; A Combination Therapy, Advanced Techniques.

Umama Yezdani, Raja Jatav, Vishal Kumar, Priyanka Priya, Mayur Sadar, Mohammad Gayoor Khan, Umama Yezdani, Shivam Choudghal, et al. (80 authors)

ARC Journal of Pharmaceutical Sciences · 2020-01

Abstract

Doctors prescribe antibiotics to kill the bacteria that cause it. need to take them for 6 to 9 months. What medications you take and how long people have to take them depends on which works to eradicate people TB. Sometimes, antibiotics used to treat the disease don't work. Doctors call this "drug-resistant" TB. If people have this form of the disease, people may need to take stronger medications for longer. It can spread to other parts of your body, like your brain and spine. A type of bacteria called Mycobacterium tuberculosis causes it. WHO fact sheet dated March 2010 on tuberculosis stated that overall one third of the world's population (over 2 billion) is currently infected with the TB bacillus. According to it, every second, someone in the world is newly infected with TB bacilli and 1 in every 10 of these newly infected people will become sick or infectious later in life. Since concurrent infection with HIV weakens the immune system, people with co-infection of HIV and TB are much more likely to develop TB; it is a leading cause of death among HIV-positive people. In Africa, HIV is the single most important factor contributing to the increase in the incidence of TB since 1990. The same fact sheet stated that in 2008, globally speaking, there were 9.37 million new cases of TB, with the African region and the Southeast Asian region (SEAR) having a share of 30% and 34%, respectively. However, the estimated incidence rate in Sub-Saharan Africa is nearly twice that in the SEAR with over 350 cases per 100,000 individuals of the human population. In the same year 2008, an estimated 1.3 million people died from TB. The highest number of deaths was in SEAR, while the highest mortality per capita was in the African region.

MeSH terms

  • Pyrazinamide
  • Ethambutol
  • Isoniazid
  • Medicine
  • Tuberculosis
  • Rifampicin
  • Antibiotics