Bacterial Colonization Pattern of Sputum in Patients Suffering From Acute Exacerbation of Chronic Obstructive Pulmonary Diseases

Background: The increased prevalence and mortality from COPD is occurring worldwide and is attributed to a rise in cigarette smoking and environmental pollution.The most common causes of an exacerbation are infection of the tracheobronchial tree and air pollution. Methods:It is a case control prospective study.This study was carried out in the indoor and outdoor of National Institute of diseases of the Chest and Hospital (NIDCH), Mohakhali, Dhaka during the period September 2010 to August 2011 on 65 patients having the diagnosis of acute exacerbation of COPD. Result: In this study sputum culture was observed and found that Pseudomonous was found 35.4%, candida in 10.8%, klebsiella in 10.8%, 6.2% was E. coli, 3.1% was streptococcus, 3.1% was s. aureus and acinetobactor, H.Influnjae, pseudomonous klebsiela & stereptococcus pneumoni was 1.5% and no growth in 23.1%. Conclusions: It would be useful to know the bacterial colonization pattern in acute exacerbation of COPD to institute earlyantibiotic administration. Pseudomonous, klebsiella, streptococcus and H.influenjae are the main pathogen in acute exacerbation of COPD whereas standard number of patient had no growth of any pathogen.