Estimation of Serum Copper and Zinc Levels among Tuberculosis Patients in Khartoum State

Background: Trace elements play an important role in tuberculosis infection because their deficiencies can be associated with impaired immunity. The aim to assessment the serum copper and zinc levels among the tuberculosis patients in Khartoum state Material: This is cross sectional study was conducted in Aboanja hospital in Khartoum state during the period from November 2016_January 2017.Citrated samples were collected from 100 study group , 50 tuberculosis patients , and 50 apparently healthy Individuals, Serum level of Zinc and Copper was measured by atomic absorption spectrometry. Result: The result is the mean level of Zinc in tuberculosis patients were significant decreased when compared with control group (P. value= <0.001) and also the mean level of Copper in tuberculosis patients significant increase when compared with group ( P. value = <0.001). Conclusion: This study showed significant decrease in level of Zinc and increase in level of Copper once compared with control group among tuberculosis patients. Keywords: Copper, Impaired immunity, Trace element, Tuberculosis, Zinc