TB Research

EP12-213-22 A systematic review of the diagnostic accuracy of Xpert MTB/RIF and Xpert Ultra for the diagnosis of tuberculous meningitis and lymph node tuberculosis in children

Alexander Kay, Lucía González Fernández, Yemisi Takwoingi, Michael Eisenhut, A K Dejten, Karen R Steingart, Anna M. Mandalakas

LSTM Online Archive (Liverpool School of Tropical Medicine) · 2020-10

Abstract

Xpert MTB/RIF and Xpert Ultra are rapid molecular tests that simultaneously detect tuberculosis in children with signs and symptoms of tuberculosis. To inform updated WHO Consolidated Guidelines on Tuberculosis Diagnosis (2020), we performed a systematic review on the diagnostic accuracy of these tests in children presumed to have TB meningitis and lymph node TB.

MeSH terms

  • Medicine
  • Tuberculosis
  • Tuberculous meningitis
  • Diagnostic accuracy
  • Tuberculosis diagnosis
  • Diagnostic test
  • Meningitis
  • Lymph node
  • Pediatrics
  • Mycobacterium tuberculosis