TB Research

[Is it possible that BCG vaccine protects against COVID-19?]

Reinout van Crevel, J.W.M. van der Meer, Mihai G. Netea

PubMed · 2020-10

Abstract

A number of clinical trials are currently underway worldwide to assess whether BCG, the old vaccine against tuberculosis, can protect against COVID-19 infection. In this Perspective, we briefly outline the background, the immunological mechanisms (in particular induction of 'innate immune memory' or 'trained immunity'), and further considerations for the potential future use of BCG against viral and other infections.

MeSH terms

  • Medicine
  • Tuberculosis vaccines
  • Coronavirus disease 2019 (COVID-19)
  • Tuberculosis
  • Immunology
  • Immunity
  • Innate immune system
  • Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
  • 2019-20 coronavirus outbreak
  • BCG vaccine
  • Virology
  • Immune system
  • Vaccination