COMPARATIVE ANALYSIS OF CYTOMORPHOLOGY PATTERNS AND AFB POSITIVITY OF LYMPH NODE ASPIRATE VS CBNAAT FOR DETECTION OF TUBERCULAR LYMPHADENOPATHY”

Background : TB remains a major health concern world wide with extrapulmonary TB accounting for 20% cases in India. Tubercular lymphadenopathy is most common extrapulmonary manifestation in TB. Aim: To compare and analyse cytomorphology patterns, AFB positivity and CBNAAT for detection of tubercular lymphadenopathy Methodology: a total of 80 FNAC samples from lymph nodes were taken, one part was sent for CBNAAT and other part was used to prepare slides and stained with H& E, PAP, MGG, ZN stain for AFB. Results:Out of 80 cases, 52 (65%)were granulomatous, 14 (17.5%)each were of reactive and suppurative. Among these 52 cases reported as granulomatous 32 were positive for CBNAAT, 11 AFB positive . Only 1 case out of 14 reactive cases was positive for CBNAAT. Out of 14 suppurative cases, 4 cases were CBNAAT positive. Conclusion: CBNAAT is a rapid test, can detect even if bacilli is less in number but FNAC along with AFB is simple procedure in resource limited area.