Is the determination of eosinophils in the induced sputum useful to assess the control of Asthmatic patient?

<b>Introduction:</b> The number of eosinophils in sputum samples, has been postulated as one of the parameters to highlight for the diagnosis and evolutionary control of asthma. Our fundamental objective is to know if there is any cut-off point that is related to worse control. <b>Material and Method:</b> Descriptive study of case series that had sputum induced between January 2016 and October 2019. <b>Results:</b> Number of patients:60. Average age:51.55 ± 13.47 years. Women:65%. Average BMI:27,78 ± 5,25. Never Smoking:71,7%. IPY:18,6 ± 15,8.Average of absolute FEV1 and %:1995,24 ± 778 cc and 69 ± 22,67%. FVC:2872 ± 949,6 cc and 78 ± 21%. Average eosinophils (Eo) in sputum:7.94 ± 11.43% and correlates with FeNO (p=0.007). Patients with eosinophils &lt;3%:43,4%, 19 with biological treatment. Blood eosinophilic count:333,62 ± 474,8, with high doses of inhaled corticosteroids (46; 78%).Having &lt; 300 Eo is related to lower FeNO (p=0.04) and higher doses of CO (p=0.01).27% treated with oral prednisone. ACT global average:16,12 ± 5,62, no significant difference from &lt;3% Eo in sputum.84.7% had no emergency care, no hospitalization (96.6%), and no ICU admissions (100%). correlation + between oral steroid cycles and sputum Eo (p=0.003).Average of IgE, FENO and Vitamin D: 357,8 ± 428,44, 34,57 ± 31,28 y 24 ± 9,16. <b>Conclusions:</b> Most had eosinophilia in their sputum, although they fell below the 3% threshold in most biologics.There is no correlation between eosinophils in sputum and in peripheral blood.Increased eosinophilia in sputum, increased need for CO rounds and increased exacerbation.Not related to disease control; related to treatment adherence.