Suboptimal moxifloxacin and levofloxacin drug exposure during treatment of patients with multidrug-resistant tuberculosis: results from a prospective study in China
Lina Davies Forsman, Katarina Niward, Johanna Kuhlin, Xubin Zheng, Rongrong Zheng, Ke Ran, Hong Chao, Jim Werngren, et al. (17 authors)
European Respiratory Journal · 2020-11
Abstract
<b>This study found target attainment of 0–55% for patients with multidrug-resistant TB using currently recommended doses of moxifloxacin (55%) and levofloxacin (0%), meaning increased doses should be considered to ensure efficacy, if safety can be assured</b> https://bit.ly/3juED6S
MeSH terms
- Levofloxacin
- Moxifloxacin
- Medicine
- Ofloxacin
- Multiple drug resistance
- Tuberculosis
- Drug
- Internal medicine
- Pharmacology
- Drug resistance
- Antibiotics