Multicenter Evaluation of the Xpert Carba-R Assay for Detection and Identification of Carbapenemase Genes in Sputum Specimens
Zhen Cai, Jia Tao, Tianye Jia, Hongyu Fu, Xin Zhang, Mei Zhao, Hong Du, Hua Yu, et al. (14 authors)
Journal of Clinical Microbiology · 2020-06
Abstract
Rapid diagnosis of infections caused by carbapenem-resistant Enterobacteriaceae (CRE) is crucial for proper treatment and infection control. The Xpert Carba-R assay is a qualitative multiplex real-time PCR method that qualitatively detects and differentiates five common carbapenemase genes ( bla KPC , bla NDM , bla VIM , bla OXA-48 , and bla IMP ) directly from rectal swabs or purified colonies within approximately 1 h.
MeSH terms
- Klebsiella pneumoniae
- Biology
- Sputum
- Microbiology
- Enterobacter aerogenes
- Enterobacter cloacae
- Citrobacter freundii
- Klebsiella oxytoca
- Enterobacteriaceae
- Carbapenem
- Serratia marcescens