TB Research

Genetic Mutations Associated with Isoniazid Resistance in Mycobacterium tuberculosis in Mongolia

Erdenegerel Narmandakh, Oyuntuya Tumenbayar, Tsetsegtuya Borolzoi, Baasansuren Erkhembayar, Tsolmon Boldoo, Naranzul Dambaa, Buyankhishig Burneebaatar, Naranbat Nymadawa, et al. (11 authors)

Antimicrobial Agents and Chemotherapy · 2020-04

Abstract

Globally, mutations in the katG gene account for the majority of isoniazid-resistant strains of Mycobacterium tuberculosis . Buyankhishig et al. analyzed a limited number of Mycobacterium tuberculosis strains in Mongolia and found that isoniazid resistance was mainly attributable to inhA mutations (B. Buyankhishig, T. Oyuntuya, B. Tserelmaa, J. Sarantuya, et al., Int J Mycobacteriol 1:40–44, 2012, https://doi.org/10.1016/j.ijmyco.2012.01.007 ).

MeSH terms

  • Isoniazid
  • INHA
  • Mycobacterium tuberculosis
  • Tuberculosis
  • Microbiology
  • Virology
  • Biology
  • Genetics