TB Research

Discovery of new polymorphs of the tuberculosis drug isoniazid

Keke Zhang, Noalle Fellah, Alexander G. Shtukenberg, Xiaoyan Fu, Chunhua Hu, Michael D. Ward

CrystEngComm · 2020-01

Abstract

Two new metastable polymorphs of the tuberculosis drug isoniazid, considered monomorphic for sixty years, were discovered using melt crystallization and nanoscale confinement.

MeSH terms

  • Isoniazid
  • Metastability
  • Tuberculosis
  • Crystallization
  • Materials science
  • Drug