TB Research

SUN-297 LEVOFLOXACIN BASED NON-RIFAMPICIN ANTI-TUBERCULOUS THERAPY- AN EFFECTIVE ALTERNATIVE IN RENAL TRANSPLANT RECIPIENTS IN RESOURCE LIMITED SETTING

Raja Ramachandran, Sahil Bagai, K L Gupta

Kidney International Reports · 2020-03

Abstract

Rifampicin is one of the most effective anti-tuberculous therapy. Rifampicin is an enzyme inducer and hence, in a post-renal transplant recipient, the dose of calcineurin inhibitors needs to be frequently monitored and modulated accordingly. In resource-limited (low- and middle-income countries) setting this is not always feasible. So, we evaluated a non-rifampicin based anti-tuberculosis therapy (ATT) using levofloxacin in kidney transplant recipients.

MeSH terms

  • Medicine
  • Rifampicin
  • Levofloxacin
  • Calcineurin
  • Tuberculosis
  • Kidney transplantation
  • Pharmacology
  • Intensive care medicine
  • Internal medicine