Hepatoprotective of Eclipta Alba Methanolic Extract in Isoniazid and Rifampicin Proved Oxidative Hepatic Injury
Aithamraju Satish Chandra, P. Shanmugapandiyan
Abstract
The current study was undertaken to evaluate the preclinical efficacy of methanolic extract of Eclipta alba (MEEA) against isoniazid and rifampicin (INH-RIF) induced hepatic injury. Animals were randomly divided in five groups, vehicle (control) or INH-RIF (50 mg/kg, i.p.) or MEEA (200 and 400mg/kg, p.o.) or standard silymarin for 28 days. INH-RIF intoxicated rats displayed significant (p
MeSH terms
- Rifampicin
- Isoniazid
- Traditional medicine
- Medicine
- Pharmacology