[¹⁸F-FDG PET/CT manifestations of massive type active pulmonary tuberculosis and its differentiation from lung cancer].

OBJECTIVE: F-FDG PET/CT findings. METHODS: F-FDG uptake (higher than mediastinal blood pool or not), radioactive defect within the lesion, and the CT findings including the lesion size, signs of cavity, vacuoles, lobulation, smooth border, and mediastinal/lung window ratio (M/L ratio) of the lesions were analyzed. Univariate and multivariate analyses were used to compare the variables between the two groups, and a logistic regression model was established for differentiation of the two diseases. The diagnostic efficiency was evaluated by area under the receiver-operating characteristic (ROC) curve analysis. RESULTS: =1/(1+e-x), X=-0.530+1.978×gender+3.343×radioactive defect +2.846×smooth border-2.116×lobulation. For diagnosis of active tuberculosis, the sensitivity, specificity, accuracy, positive predictive value and negative predictive value of this model were 78.4%, 92.2%, 84.8%, 92.1%, and 78.7%, respectively. CONCLUSIONS: F-FDG uptake alone has only limited value for a differential diagnosis.