TB Research

Formulation and evaluation of β-cyclodextrin-mediated inclusion complexes of isoniazid scaffolds: molecular docking and <i>in vitro</i> assessment of antitubercular properties

Lincy Tom, Christy Rosaline Nirmal, Azger Dusthackeer, B. Magizhaveni, M.R. Prathapachandra Kurup

New Journal of Chemistry · 2020-01

Abstract

Inclusion complexes of isoniazid derivatives with β-CD were synthesized and their potent antitubercular properties were studied.

MeSH terms

  • Chemistry
  • Cyclodextrin
  • Docking (animal)
  • In vitro
  • Isoniazid
  • Combinatorial chemistry