Prevalence and clinical characteristics of Diabetes in Tuberculosis patients in Newham

Background. There is substantial evidence of the increasing burden of diabetes mellitus (DM) posing a threat to tuberculosis (TB) control globally. The global estimate of DM is expected to reach 592 million by 2030. In Europe, the estimated prevalence of DM is 8.5% and the rate of TB is 40 cases per 100,000 persons, with 74, 000 new cases per year (Badawi et al., 2014). It is estimated that DM triples the risk of developing TB when exposed an actively infected TB case, as well as modify the presenting features of TB, with more atypical radiological presentation, adverse TB treatment outcome, increased rates of relapse rates and death. The UK has the highest number of cases of TB in Western Europe. The London Borough of Newham has the highest number of cases in the UK, and this poses a public health risk. Thus, this research is aimed at analysing the prevalence of DM in TB patients in Newham and to describe the clinical presentation of Tuberculosis-Diabetes Mellitus (TB-DM) patients. Aim and objectives. The major objectives: 1. To determine the prevalence of DM in TB patients in Newham, with close attention paid to differences between UK-born and non-UK born patients; 2. To analyse the demographic, clinical ... (continues)