TB Research

Diagnostic efficacy of EBUS-TBNA in benign diseases in a population with a high prevalence of tuberculosis

Batum Ö, Katgı N, Özdemir Ö, Yılmaz U

Diagnostic cytopathology · 2020-11

Abstract

Setting Although endobronchial ultrasonography-transbronchial needle aspiration (EBUS-TBNA) has a well-known place in the staging and diagnosis of lung cancer, the place of EBUS is not clear in the diagnosis of benign diseases, especially in countries with a high prevalence of tuberculosis. Aim The aim of this study is to investigate the diagnostic efficacy of EBUS-TBNA in benign diseases in a population with a high prevalence of tuberculosis. Material and methods Between October 2011 and March 2018, 1077 EBUS-TBNA was applied. Results The diagnosis was reached with mediastinoscopy or video assisted thoracic surgery (VATS) in 41 (74.5%) and with the second EBUS-TBNA performed in 14 (25.5%) of 55 EBUS practices in 41 patients with malignancy diagnosis. The final diagnosis was achieved with clinical/radiological features in 7 (77.7%) cases of sarcoidosis, with VATS/mediastinoscopy in 2 (22.2%) cases, with EBUS-TBNA performed for the second time in 6 (54.5%) tuberculosis cases and with acid-resistance bacilli reproduction in Lowenstein-Jensen culture in 5 (45.4%) cases. Two hundred and ninety-five (79.7%) patients were accepted as "benign disease" due to the absence of radiological and clinical progression of lesions in the follow-up. Conclusion The diagnostic accuracy of EBUS-TBNA is high in benign diseases such as sarcoidosis and tuberculosis.

MeSH terms

  • Mediastinum
  • Humans
  • Tuberculosis
  • Lung Neoplasms
  • Neoplasm Staging
  • Prevalence
  • Retrospective Studies
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Middle Aged
  • Female
  • Male
  • Young Adult
  • Endoscopic Ultrasound-Guided Fine Needle Aspiration