TB Research

Non-tuberculosis Mycobacterium Tenosynovitis with Rice Bodies in a Patient with Systemic Lupus Erythematosus

Fujieda Y, Ninagawa K, Matsui Y, Kono M, Kamishima T, Iwasaki N, Atsumi T

Internal medicine (Tokyo, Japan) · 2020-06

Abstract

Infectious disease with various presentations in systemic lupus erythematosus often resembles lupus flare. A 37-year-old woman presented with a swollen left index finger that had not resolved, despite 7 years of immunosuppressive treatment. MRI showed rice-body formation in the flexor tendon sheath and tenosynovectomy demonstrated chronic synovitis with epithelioid granuloma. A mycobacterial culture confirmed invasive mycobacterial tenosynovitis due to Mycobacterium chelonae. The patient was treated with moxifloxacin and clarithromycin and completely recovered.

MeSH terms

  • Fingers
  • Humans
  • Mycobacterium Infections
  • Tenosynovitis
  • Lupus Erythematosus, Systemic
  • Clarithromycin
  • Anti-Bacterial Agents
  • Magnetic Resonance Imaging
  • Adult
  • Female
  • Symptom Flare Up
  • Moxifloxacin