TB Research

Prevalence of nontuberculous mycobacteria in a tertiary hospital in Beijing, China, January 2013 to December 2018

Huang JJ, Li YX, Zhao Y, Yang WH, Xiao M, Kudinha T, Xu YC

BMC microbiology · 2020-06

Abstract

Background To investigate the species distribution of non-tuberculous mycobacteria (NTM) among tuberculosis (TB) specimens collected from January 2013 to December 2018 at Peking Union Medical Hospital (Beijing), China. NTM species identification was carried out by DNA microarray chip. Results Mycobacterial species were detected in 1514 specimens from 1508 patients, among which NTM accounted for 37.3% (565/1514), increasing from a proportion of 15.6% in 2013 to 46.1% in 2018 (P Conclusion The proportion of NTM among mycobacterial species detected in a tertiary hospital in Beijing, China, increased rapidly from year 2013 to 2018. Middle-aged patients are more likely to be infected with NTM, especially females. Mycobacterium intracellulare and Mycobacterium chelonae/ Mycobacterium abscessus were the most frequently detected NTM pathogens. Accurate and timely identification of NTM is important for diagnosis and treatment.

MeSH terms

  • Respiratory System
  • Lymph Nodes
  • Humans
  • Suppuration
  • DNA, Bacterial
  • Oligonucleotide Array Sequence Analysis
  • Prevalence
  • Retrospective Studies
  • Age Factors
  • Adult
  • Middle Aged
  • China
  • Female
  • Male
  • Mycobacterium Infections, Nontuberculous
  • Nontuberculous Mycobacteria
  • Tertiary Care Centers