TB Research

The Use of Optical Coherence Tomography Angiography in the Diagnosis of Inflammatory Type 1 Choroidal Neovascularization Secondary to Tuberculosis: A Case Report

Demirel S, Yalçındağ N, Yanık Ö, Batıoğlu F, Özmert E

Ocular immunology and inflammation · 2020-05

Abstract

Purpose : To report a case of choroidal neovascularization (CNV), which was not obvious with dye angiography but was detected with optical coherence tomography angiography (OCTA). Methods : A 50-year-old female presented with decreased vision in her right eye. Funduscopic examination revealed a swollen hyperemic disc, peripapillary exudation, and choroidal infiltration. Results : Optical coherence tomography revealed intraretinal cysts, subretinal fluid in the macular region, and subretinal hyperreflective material in the papillomacular area. Fluorescein angiography revealed early hypofluorescence in the areas of choroidal infiltrations, and indocyanine green angiography (ICGA) also showed hypocyanescence corresponding to these infiltrations and revealed a faint hypocyanescence in the papillomacular region, further corresponding to the subretinal hyperreflective material on OCT scan. Two weeks after the initiation of systemic therapy with the diagnosis of tuberculosis, OCTA scans detected Type 1 CNV in the peripapillary area. Conclusion : OCTA may be superior to ICGA in the detection of CNV secondary to inflammatory situations.

MeSH terms

  • Humans
  • Tuberculosis, Ocular
  • Cysts
  • Retinal Diseases
  • Choroidal Neovascularization
  • Choroiditis
  • Indocyanine Green
  • Glucocorticoids
  • Antitubercular Agents
  • Tomography, Optical Coherence
  • Fluorescein Angiography
  • Visual Acuity
  • Middle Aged
  • Coloring Agents
  • Female
  • Subretinal Fluid
  • Interferon-gamma Release Tests
  • Computed Tomography Angiography