Diagnostic Accuracy of QuantiFERON-TB Gold Plus Assays in Children and Adolescents with Tuberculosis Disease
Soler-Garcia A, Gamell A, Santiago B, Monsonís M, Calvo C, Cobo E, Colino E, Espiau M, et al. (20 authors)
The Journal of pediatrics · 2020-04
Abstract
In 2016, a new interferon-gamma release assay, QuantiFERON-TB Gold Plus, was introduced. We conducted a cross-sectional multicenter study, involving 158 children and adolescents with tuberculosis disease. The overall sensitivity of the assay was 82.9% (IQR 77.0%-88.8%), indicating that in children this test does not have higher sensitivity than previous generation interferon-gamma release assays.
MeSH terms
- Humans
- Mycobacterium tuberculosis
- Tuberculosis
- Tuberculin Test
- Retrospective Studies
- Follow-Up Studies
- Adolescent
- Child
- Child, Preschool
- Female
- Male
- Interferon-gamma Release Tests