Development of <i>Mycobacterium avium</i> Complex Lung Disease in Patients With Lung Cancer on Immune Checkpoint Inhibitors
Fujita K, Yamamoto Y, Kanai O, Okamura M, Nakatani K, Mio T
Open Forum Infectious Diseases · 2020-03
Abstract
Immunotherapy with immune checkpoint inhibitors (ICIs), while ameliorating lung cancer, can cause infectious diseases, including tuberculosis, in addition to immune-related noninfectious complications. In the clinical setting, the efficacy of ICIs to treat mycobacterial infection remains controversial. We report 3 cases of acute Mycobacterium avium complex lung disease during immunotherapy with ICIs.