A Long-Term Follow-up of Retinal Vasculitis - Do They Develop Systemic Disease?
Kawali A, Bavaharan B, Sanjay S, Mohan A, Mahendradas P, Shetty B
Ocular immunology and inflammation · 2020-01
Abstract
Purpose : To study systemic association and relapses in a long-term follow-up of primary retinal vasculitis (PRV) and possible tubercular vasculitis (PTV) cases. Method : Retrospective, descriptive chart review of patients diagnosed as PRV and PTV with ≥1-year follow-up. Clinical presentation, systemic association, morphology of vasculitis, relapses, and treatment were noted. Results : 123 eyes of 76 patients were studied. Occlusive (n = 97), exudative (n = 16), combined (n = 10) and focal (n = 7) vasculitis were seen. Vitreous hemorrhage at presentation was noted in 27% eyes (n = 33). Four patients (3.25%) developed systemic disease during follow-up (2 psoriasis, 1 Systemic Lupus Erythematosus, 1 ulcerative colitis). Mean number of cases with relapses were 45 (59.21%). Number of cases with relapses in PRV and PTV were 20 (66.66%) and 16 (66.66%), respectively. ( p = 1) Conclusion : Systemic disease attributed to vasculitis can rarely develop during follow up of PRV and PTV patients. Relapses remain almost same in PTV and PRV.
MeSH terms
- Humans
- Tuberculosis, Ocular
- Colitis, Ulcerative
- Vitreous Hemorrhage
- Retinal Vasculitis
- Lupus Erythematosus, Systemic
- Psoriasis
- Recurrence
- Methotrexate
- Azathioprine
- Cyclosporine
- Immunosuppressive Agents
- Glucocorticoids
- Antitubercular Agents
- Fluorescein Angiography
- Tuberculin Test
- Drug Therapy, Combination
- Retrospective Studies
- Follow-Up Studies
- Visual Acuity
- Adolescent
- Adult
- Aged
- Middle Aged
- Female
- Male