Faculty Opinions recommendation of Pharmacokinetics, optimal dosing, and safety of linezolid in children with multidrug-resistant tuberculosis: Combined data from two prospective observational studies.
Brian Eley
Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · 2019-09
Abstract
Linezolid is increasingly important for multidrug-resistant tuberculosis (MDR-TB) treatment. However, among children with MDR-TB, there are no linezolid pharmacokinetic data, and its adverse effects have not yet been prospectively described. We characterised the pharmacokinetics, safety, and optimal dose of linezolid in children treated for MDR-TB.
MeSH terms
- Linezolid
- Observational study
- Dosing
- Pharmacokinetics
- Medicine
- Tuberculosis
- Pharmacology