The Antibacterial Activity of a Fraction Extracted from Camel Urine against Mycobacterium tuberculosis Isolated from Tuberculosis Patients in Jeddah City
Raniya Sami Bakhsh, Samah O. Noor, A. Mohamed Nora Faten, Ahmed Faten, Abdulwahab Alzahrani, Azhar Najjar, Ahmed M. Al-Hejin, Azhar Najjar, et al. (61 authors)
Advances in Environmental Biology · 2019-01
Abstract
Mycobacterium tuberculosis bacteria (MTB) that causes Tuberculosis (TB) disease and determine the period of treatment required for effectiveness comparing with Rifampicin (RIF) antibiotic. This study depended on an experimental design that used 10 random samples of MTB from King Fahad Armed Hospital (KFAH) Processed. The study was conducted in two auto-analyzer systems BACTEC 960 culture system and GeneXpert MTB/RIF assay with five different PMF concentrations. In total, all concentrations of PMF drug except 10% compared with the RIF antibiotic, showed some effectiveness on MTB. In summary, these results showed a non-significant effect of the PMF concentrations except 10% that indicated as the ideal concentration of this drug that reduces the number of bacteria. Further statistical tests revealed the P-value of the F test was less than 0.05 %. Overall, these results indicate no complete effect comparison between growth control of MTB treated with RIF and treated with PMF except 10% that need further studies.
MeSH terms
- Tuberculosis
- Rifampicin
- Mycobacterium tuberculosis
- GeneXpert MTB/RIF
- Bacteria
- Microbiology
- Urine
- Antibiotics
- Antimicrobial
- Medicine
- Biology