Study the Clinical, Radiological and Microbiological Profile of Patients with Bronchiectasis in a Tertiary Care Hospital

INTRODUCTION: Bronchiectasis has prevalence of 4.2 per 1,00,000 persons. Patients are prone to recurrent LRTI & derailment of pulmonary functions which leads to poor QLI. It is considered more of an orphan disease without much research work. This study aims to bring out their clinical, radiological & microbiological features, their correlation with each other, for early disease identification, treatment and prevention of complications. AIM: To study the: Bronchiectasis patients socio-demographic, clinical, radiological and microbiological profile. Causative organism and its’ radiological correlation/disease severity MATERIALS AND METHODS: Its’ a cross sectional study with 165 patients for 6 months. History, clinical examination, symptom analysis, X-ray, HRCT chest, PFT (spirometry), ECHO, Sputum AFB, gram staining, culture &sensitivity done. RESULTS: 78-males and 87 females.36.4% in age group of 40-50yrs and 33.7% in 50-60yrs. 52% had cough with sputum, 23% with cough, 49% with breathlessness. Etiology couldn’t be identified in 39%, while 32.7% had prior ATT. 45.5% had obstruction in PFT, while 38.8% was normal. Radiologicaly bilateral involvement was seen in 30% with cylindrical being common type in 58.8%. 42.7% had 2 lobe involvement and 1.8% had involvement of all lobes. 22.4% had hemoptysis. PHT and corpulmonale seen in 10.3% & 9.7% respectively Pseudomonas and klebsiella were common organisms in 26% each, E.coli and H.influenza in 18.2% and 10.3% respectively. Increased number of lobes involvement and destructive cystic types had signification correlation with pseudomonas culture (p < 0.001). CONCLUSION: Bronchiectasis is a progressive disease with increased morbidity and mortality. While RADIOLOGY plays an important role in diagnosis, MICROBIOLOGY plays an important role in treatment and preventing exacerbations/disease progression. Hence a multidisciplinary assessment is essential for wholesome management of the disease