TB Research

Rapid detection of difficult-to-culture bacterial pathogens using real-time nanopore sequencing

Aycan Gündoğdu, Ayşegül Ulu-Kılıç, Hüseyin Kılıç, Özkan Ufuk Nalbantoğlu

Infectious Diseases and Clinical Microbiology · 2019-12

Abstract

Infectious diseases are the leading causes of mortality and morbidity worldwide. Current diagnosis of clinically significant infectious agents is based on a variety of laboratory-based tests including microscopy, culture, immunoassays and nucleic acid amplification. The majority of these techniques relies on conventional culture-based profiling […]

MeSH terms

  • Nanopore sequencing
  • Metagenomics
  • Microbiological culture
  • Nanopore
  • Brucellosis
  • Medicine
  • Molecular diagnostics
  • Tuberculosis
  • Computational biology
  • Microbiology
  • Biology
  • DNA sequencing
  • Virology