TB Research

Simultaneous Determination of Isoniazid, Pyrazinamide and Rifampin in Human Plasma by High-performance Liquid Chromatography and UV Detection.

Behnam Dasht Bozorg, Ali Goodarzi, Fanak Fahimi, Payam Tabarsi, Nahid Shahsavari, Farzad Kobarfard, Farzaneh Dastan

PubMed · 2019-01

Abstract

for INH, PZA, and RIF, respectively. The method presented here was selective, sensitive, and reproducible, and could be used for‌ therapeutic drug monitoring in the patients who were under treatment with these drugs.

MeSH terms

  • Pyrazinamide
  • Chromatography
  • Isoniazid
  • Protein precipitation
  • Therapeutic drug monitoring
  • High-performance liquid chromatography
  • Detection limit
  • Chemistry
  • Drug