An Observational Study to Evaluate role of Serum Immunoglobulin Levels as potential markers in tuberculosis diagnosis

Method: Sixty patients were recruited as in this study who were diagnosed as tuberculosis patients from Patna Medical College and hospital at Patna. This diagnosis was done on the basis of patient history, clinical examination, sputum examination, chestradiography and related laboratory parameters. This patients were compared with fifty five healthy volunteers who were matched with age and sex. Blood sample were collected to measure the levels of IgA, IgM, IgE at hospital laboratory. Result: When compared with normal healthy volunteers, levels of IgA, IgM, IgE were found to be increased significantly (p<0.001). There was significant increase in serum immunoglobulin levels observed among TB patients as compare to healthy volunteers. Conclusion: May be due to humoral response to mycobacterial antigens, this Serum Immunoglobulin Levels were elevated in tuberculosis patients as compare to healthy volunteers.